Body composition, considered.
Metabolic & Weight Optimisation
A structured, doctor-led approach to body composition and metabolic health, combining GLP-1 medications, peptides, BHRT, and lifestyle support within a personalised plan.
Wellness & Longevity · London & Dubai
The Treatment
Metabolic & Weight Optimisation
Metabolic & Weight Optimisation at 23MD is a structured medical programme designed to address body composition, metabolic health, and the underlying drivers of weight gain, not a single prescription. Depending on your individual assessment, the programme may include GLP-1 medications (such as Mounjaro or Wegovy), peptide protocols, BHRT, and lifestyle integration.
GLP-1 medications such as Mounjaro and Wegovy have transformed what is possible in medical weight loss. But they are not a strategy on their own. Patients who do well long-term are the ones who use the medication within a structured programme, protecting lean mass, optimising hormones, addressing the lifestyle drivers of weight gain, and planning carefully for what happens when the medication is reduced or stopped. The medication is one tool. The plan is the treatment.
About
What it is, how it works.
How it works
The programme begins with a comprehensive medical consultation, full bloodwork, and a body-composition assessment. From there, your doctor builds a plan around the tools most appropriate to your physiology, goals, and risk profile. GLP-1 medications, where appropriate, are prescribed and monitored within the programme, not as a standalone treatment. Hormones, peptides, and lifestyle support are layered in where they add clinical value.
Why it matters
GLP-1 medications such as Mounjaro and Wegovy have transformed what is possible in medical weight loss. But they are not a strategy on their own. Patients who do well long-term are the ones who use the medication within a structured programme, protecting lean mass, optimising hormones, addressing the lifestyle drivers of weight gain, and planning carefully for what happens when the medication is reduced or stopped. The medication is one tool. The plan is the treatment.
Indications
What We Treat
- Persistent weight that has not responded to lifestyle change
- Body composition concerns, central fat or loss of lean mass
- Metabolic markers drifting in the wrong direction
- Perimenopausal or post-menopausal weight change
- Andropause and age-related metabolic decline
- Patients who started GLP-1 medications elsewhere without a wider plan
Results & Expectations
Clinical Expertise. Natural Outcomes.
What may improve
- Body composition, fat mass, lean mass, body fat percentage
- Metabolic markers (where relevant)
- Energy, sleep, and overall function
- Sustainable long-term outcomes built into maintenance
- Quality and longevity of aesthetic outcomes
Timeline
Some effects within weeks. Meaningful body composition change typically develops across months. Long-term sustainability depends on the maintenance plan.
We do not promise weight-loss numbers; we deliver a programme.
Meet the 23MD Digital Team
Doctor-led intelligence, at your fingertips. Explore whether Metabolic & Weight Optimisation is the right pathway with our BHRT Digital Doctor.
Suitable For
Safety & Suitability
Not suitable for
- Pregnancy, breastfeeding, or active attempts to conceive
- Personal/family history of medullary thyroid carcinoma or MEN-2
- Active or recent severe gastrointestinal disease
- Certain endocrine, cardiovascular, or pancreatic conditions
- Patients seeking weight loss without commitment to monitoring
- Active eating disorders (assessed individually)
Consultation required: A comprehensive medical consultation, full history, and appropriate bloodwork are required before any GLP-1, peptide, or hormonal protocol is initiated.
FAQs
Your Questions, Answered
Medically reviewed by Dr Suha Kersh, MBBS, GMC-registered on April 2026.
