At 23MD, we specialise in helping you tap into cutting-edge anti-aging treatments, and we always aim to provide clear and transparent advise. One of the most exciting areas of research today is the role of NAD+ (nicotinamide adenine dinucleotide) in reversing the signs of aging. NAD+ is crucial for energy production, cellular repair, and metabolism. A powerful way to boost your NAD+ at 23MD  is simply through an oral supplement called NMN (nicotinamide mononucleotide).

While many clinics are providing  intravenous (IV) NMN therapy, we encourage oral NMN supplementation as a highly effective, non-invasive way to boost your NAD at 23MD. This is especially because of the positive impact of NMN and NAD  in supporting gut health by supporting your gut microbiome. Beyond its role in making NAD+, NMN molecules have their own health benefits. NMN supplements can aid your body’s insulin production and glucose tolerance. They have positive effects on overall metabolism as well.

Why Boost Your NAD+ at 23MD with NMN?

NAD+ is a vital coenzyme that declines with age, contributing to decreased energy levels, slower metabolism, and even age-related diseases. By supplementing with NMN, your body can naturally produce more NAD+. NMN is a precursor of NAD, found in small quantities in foods like avocados, broccoli, and tomatoes, but to take even 150 mg of NMN daily, you’d need to consume around 12,000 edamame beans or 2,400 heads of broccoli! This makes supplementation a more practical and efficient solution. At 23MD, we advise using  NMN as an oral supplement rather then NAD intravenously, to improve not only your cellular health, but also your gut microbiome at the same time.

What are the Benefits of NAD+ optimisation using Oral NMN

• Improved Insulin Sensitivity: Studies show that NMN can increase insulin sensitivity, benefiting those with metabolic concerns like prediabetes.
• Gut Health Benefits: Oral NMN interacts with the gut, potentially supporting a healthier microbiome, which is crucial for digestion, immunity, and mental well-being.
• Anti-Inflammatory Effects: NAD+ helps reduce inflammation at the cellular level, which is key to preventing age-related diseases and maintaining overall health.
• Support for Brain Health: NMN’s role in boosting NAD+ levels is linked to improved cognitive function, memory, and overall brain health.
• Enhanced Muscle Function: NMN helps maintain muscle strength and function by supporting NAD+ production, essential for muscle regeneration.
• Cardiovascular Support: NMN has been shown to promote better cardiovascular health by improving blood flow and supporting heart function.
• Longevity and Anti-Aging: Boosting NAD+ with NMN may help slow the aging process, promoting longevity and overall vitality.

Oral NMN vs. Intravenous: Why the Gut Matters

One of the reasons we recommend oral NMN supplementation over IV therapy is the interaction it has with your digestive system, and, more specifically, your gut microbiome. Oral NMN passes through your gut, where it has the potential to benefit the microbiome, a critical element in your overall health and well-being. By choosing oral NMN, you not only boost your NAD at 23MD, but you also support the intricate balance of bacteria in your digestive system, which plays a key role in immune function and even mental health.

Studies have shown that different tissues and organs may prefer NMN as a precursor to NAD+ over others, such as NR (nicotinamide riboside). NMN is a more direct precursor, making it a better option for maximizing NAD+ production throughout your body, including your gut.

Scientific Support for NMN Benefits

Research supports the use of NMN for improving metabolic health and boosting insulin sensitivity.

One study demonstrated that taking 250 mg of NMN per day for 10 weeks significantly increased insulin sensitivity in postmenopausal women with pre-diabetes. This makes NMN a great choice not only for improving energy and cellular function but also for metabolic health as we age.

This 2024 study,  Biochemical and Biophysical Research Communications, found that NMN supplementation enhances NAD+ levels. It also helps to combat the effects of oxidative stress, which is a major contributor to aging .

How Much NMN Do You Need to Boost Your NAD at 23MD?

Studies have found that doses as low as 250 mg per day are sufficient to see significant health benefits. NMN supplementation can safely and effectively boost NAD+ levels, improving energy production, metabolism, and even supporting DNA repair. Oral NMN is easy to incorporate into your daily routine. Taken as a supplement, it is an easy and  convenient way to maintain  your NAD+ levels and overall health.

Boost Your NAD at 23MD with Oral NMN for Optimal Gut Health

At 23MD, we are dedicated to providing anti-aging solutions that go beyond the surface. Oral NMN supplementation offers a powerful and practical way to boost your NAD levels while supporting your gut microbiome. The digestive system plays a critical role in overall health. Oral NMN ensures you’re not just supporting your cells, but also promoting a healthier gut.

At 23MD , we’re here to guide your journey to optimal health and longevity, always providing clear and transparent advice . COntact us here if you need more information

References

1. Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women
2. Understanding NAD