8 April 2025

    Polynucleotides Under Eye Treatment at 23MD London and Dubai

    For years, tear trough fillers were the go-to treatment, but for many, the results were unpredictable. Overfilling, puffiness, Tyndall effect (a bluish hue un

    A woman's face with the under-eye area marked for treatment illustrating an archived health article at 23MD

    For years, tear trough fillers were the go-to treatment, but for many, the results were unpredictable. Overfilling, puffiness, Tyndall effect (a bluish hue under the skin), or an unnatural look often left patients disappointed. That’s why 23MD has pioneered a more sophisticated, regenerative approach: Polynucleotides under Eye Treatment.

    At 23MD Clinics in London and Dubai, we understand that the under-eye area is one of the most delicate and emotionally charged regions of the face. From dark circles and puffiness to thinning skin and hollowness, tear trough concerns can make even the most vibrant individuals appear tired or prematurely aged.


    What Are Polynucleotides?

    Polynucleotides are bio-stimulating molecules derived from purified salmon DNA, the same building blocks that form DNA and RNA in our bodies. When injected into the under-eye area, polynucleotides regenerate the skin from within by stimulating fibroblast activity, boosting collagen and elastin production, and enhancing tissue repair.

    This treatment also improves microcirculation and skin hydration, brightening the tear troughs and softening dark circles without adding volume. At 23MD, we describe this approach as treating the root cause rather than masking the symptoms.


    Why We Prefer Polynucleotides Over Fillers for the Under-Eye Area

    Although hyaluronic acid (HA) fillers can work well in some cases, they pose challenges when used under the eyes due to the thinness of the skin and limited lymphatic drainage in this area. Risks include:

    • Persistent puffiness or swelling

    • Tyndall effect (bluish discoloration)

    • Overfilling and a “done” appearance

    • Migration or heaviness

    Polynucleotides offer a non-volumising, regenerative solution. They improve skin quality naturally, without the risk of heaviness or artificial-looking results.


    23MD: A Centre of Excellence for Polynucleotide Tear Trough Treatments

    At 23MD Clinics in Dubai and London, we are proud to be recognised as a centre of excellence in regenerative aesthetic medicine. Our team of expert doctors uses a layered, personalised approach to tear trough rejuvenation, making polynucleotides a cornerstone of our under-eye protocols.

    Our treatment is ideal for:

    • Dark circles and under eye shadowing

    • Thin, crepey under-eye skin

    • Early signs of hollowing

    • Post-filler correction or migration

    • Patients seeking non-volume-based solutions

    Whether you are visiting our state-of-the-art clinic in London’s medical district or our flagship Dubai aesthetic clinic, you’ll receive a bespoke treatment plan delivered with precision, care, and artistry.


    “Bright-Eyed and Salmon-Tailed”: The 23MD Philosophy

    At 23MD, we say our patients leave “bright-eyed and salmon-tailed”, a nod to the salmon DNA used in polynucleotide treatments and the vibrant, well-rested appearance that follows. This treatment doesn’t make you look “done.” It makes you look subtly refreshed.

    Our patients often share:

    “People keep asking if I’ve been on holiday.”
    “My eyes look softer and brighter, but nobody can tell what I’ve had done.”
    “It’s the first time a treatment worked without making me look puffy.”

    This is the regenerative magic of polynucleotides: subtle, biological, and profoundly natural.


    Who Can Benefit from Polynucleotide Tear Trough Treatments?

    This treatment is suitable for a wide range of individuals, including:

    • Young adults looking to prevent early signs of ageing

    • New mothers with fatigued, delicate under-eyes

    • Mid-life patients seeking natural rejuvenation

    • Patients correcting or recovering from filler treatments

    Whether you’re exploring tear trough treatments in Dubai or seeking a non-filler solution in London, 23MD offers world-class expertise backed by science and artistry.


    Book Your Consultation at 23MD London or Dubai for Polynucleotides Under Eye Treatment

    Polynucleotide tear trough rejuvenation is one of our most requested, and most expertly delivered, treatments. At 23MD, we are dedicated to offering regenerative solutions that work in harmony with your body, not against it.

    Book your consultation today at 23MD London or Dubai and experience why we are the leading clinic for natural, polynucleotide-based under-eye rejuvenation.

    Medically reviewed by Dr Suha Kersh, MB BCh BAO LRCP&SI, MRCPsych, GMC-registered since 1992.

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    What our patients say

    Verified feedback from 23MD patients, collected after their appointments through our clinic system and published with permission.

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    “Dr. Galy was very professional and listened to all my concerns. He explained everything so that I could understand. I felt confident in his treatment plan.”

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    Dr Martin Galy

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