Bioremodelling, quietly powerful.
Profhilo
A doctor-led injectable that does more than hydrate, it remodels the skin, supporting elasticity, firmness, and quality from within.
Injectables · London & Dubai
The Treatment
Profhilo
Profhilo is one of the most considered injectables in modern aesthetic medicine. It looks like a Skin Booster, but does something more sophisticated: rather than simply hydrating, it remodels the skin from within, supporting elasticity, firmness, and quality at a deeper level.
Skin laxity is one of the harder concerns in aesthetic medicine to address subtly. Lifting devices can be aggressive; surgery is too far for many patients; topical creams rarely move the needle. Profhilo sits in a quiet middle space, a doctor-delivered, well-evidenced treatment that improves skin quality and firmness without changing shape, and without downtime.
Duration
20–30 min
Downtime
24–48 hrs
Pain level
Low
Sessions
2 sessions, then every 6 months
Results start
Week 2
Results peak
8 weeks
About
What it is, how it works.
How it works
Profhilo is delivered through a small number of precise injection points across the treatment area. From these points, the gel spreads naturally beneath the skin and slowly releases pure hyaluronic acid, which stimulates the cells responsible for collagen and elastin. Over the following weeks, the skin gradually behaves more like younger skin, firmer, more elastic, more hydrated.
Why it matters
Skin laxity is one of the harder concerns in aesthetic medicine to address subtly. Lifting devices can be aggressive; surgery is too far for many patients; topical creams rarely move the needle. Profhilo sits in a quiet middle space, a doctor-delivered, well-evidenced treatment that improves skin quality and firmness without changing shape, and without downtime.
Indications
What We Treat
- Loss of skin firmness or elasticity
- Crepey or thinning skin
- Dull or dehydrated-looking skin
- Skin laxity in the lower face, neck, and décolletage
- Crepey skin on the hands
- Early signs of skin ageing
Practitioners
Your Experts
Treatment Stacking™
Combines beautifully with
Results & Expectations
Clinical Expertise. Natural Outcomes.
What may improve
- Skin firmness and elasticity
- Hydration and surface smoothness
- Overall skin tone and radiance
- Skin quality in the lower face, neck, décolletage, and hands
Timeline
Initial improvement from week 2; peak outcomes approximately 8 weeks after the second session. Maintenance every 6 months.
Profhilo improves skin quality and firmness, it does not change facial shape or proportion.
Meet the 23MD Digital Team
Doctor-led intelligence, at your fingertips. Explore your skin or plan how Profhilo layers with the rest of your protocol.
Skin Analyser
AI-led skin assessment
Upload a photo and receive a personalised skin assessment with treatment recommendations from our doctor-led protocols.
Analyse My SkinTreatment Stacker
Build your optimal protocol
An intelligent planner that layers aesthetic, regenerative and longevity treatments into a sequenced protocol calibrated to your goals and timeline.
Build My Treatment StackSuitable For
Safety & Suitability
Not suitable for
- Pregnancy or breastfeeding
- Active skin infection in the treatment area
- Known hypersensitivity to hyaluronic acid
- Certain autoimmune conditions
- Active inflammatory skin disease
Consultation required: A medical consultation is required before treatment to confirm suitability and design the appropriate course.
FAQs
Your Questions, Answered
Medically reviewed by Dr Suha Kersh, MBBS, GMC-registered on April 2026.




