Regenerate · Sustain · Compound
The Second Skin Protocol
Our signature facial regeneration programme — a doctor-led, multi-session course delivered across three months to compound the response of the skin.
Signature Programme · London & Dubai
The Treatment
The Second Skin Protocol
The Second Skin Protocol is a three-month, doctor-led course of regenerative facial treatments. It combines microneedling, polynucleotides, skin boosters and LED across a defined sequence, designed to compound the skin's repair response rather than rely on a single visit.
Skin doesn't change in a single session — it changes when the right stimulus is repeated at the right interval. The Second Skin Protocol is built around that biology, replacing isolated treatments with a defined regenerative arc.
Duration
60–90 min
Downtime
12–24 hrs
Pain level
Low
Sessions
12-week course
Results start
After 2 sessions
Results peak
8–12 weeks
About
What it is, how it works.
How it works
Treatments are scheduled at structured intervals across twelve weeks. Early sessions focus on initiating the repair cascade and supporting hydration; mid-course sessions deepen collagen response; later sessions consolidate and protect the result. Your treating doctor reviews progress between phases and adjusts the protocol as the skin responds.
Why it matters
Skin doesn't change in a single session — it changes when the right stimulus is repeated at the right interval. The Second Skin Protocol is built around that biology, replacing isolated treatments with a defined regenerative arc.
Indications
What We Treat
- Long-term loss of skin quality, tone and bounce
- Texture, pores and surface irregularity
- Sun damage and uneven pigmentation
- Post-pregnancy or post-menopausal skin changes
- Patients ready to commit to a structured regenerative course
Practitioners
Your Experts
Results & Expectations
Clinical Expertise. Natural Outcomes.
What may improve
- Collagen quality and bounce
- Texture, pore size and clarity
- Hydration and skin resilience
- Overall tone and evenness
Timeline
Visible change from the first sessions; peak result 8–12 weeks after the final session. Maintenance typically quarterly thereafter.
Results vary with skin condition, hormonal status and adherence to the protocol and aftercare.
Meet the 23MD Digital Team
Doctor-led intelligence, at your fingertips. Explore your skin or plan how The Second Skin Protocol layers with the rest of your protocol.
Skin Analyser
AI-led skin assessment
Upload a photo and receive a personalised skin assessment with treatment recommendations from our doctor-led protocols.
Analyse My Skin
Treatment Stacker
Build your optimal protocol
An intelligent planner that layers aesthetic, regenerative and longevity treatments into a sequenced protocol calibrated to your goals and timeline.
Build My Treatment StackSuitable For
Safety & Suitability
Not suitable for
- Pregnancy or breastfeeding
- Active inflammatory skin disease in the treatment area
- Recent isotretinoin use (within 6 months)
- Patients unable to commit to the full course schedule
Consultation required: A clinical consultation or Foundation Reset is required to confirm suitability and tailor the protocol.
FAQs
Your Questions, Answered
Medically reviewed by Dr Suha Kersh, MBBS, GMC-registered on April 2026.
